Dosing frequency is how often the body is exposed to a dose pattern, which can matter more than raw amount.
Why it matters
Compound class and half-life often shift outcomes more than a single number alone.
Practical frequency logic by class
- Daily compounds: typically paired with lower-intensity maintenance pacing.
- Split-dose compounds: used where sustained exposure is needed, often with measurable trough effects.
- Loading bursts: time-limited higher frequency for rapid re-establishment.
Avoid combining multiple “daily” compounds into one megadose unless your log evidence supports that tolerance.
Circadian and half-life effects
- Daily routines should align with wake and sleep goals.
- Short half-life compounds often need spacing; longer half-life compounds can drift into accumulation if stacked too tightly.
Anti-pattern examples
- stacking loading bursts across unrelated compounds,
- packing all “daily” compounds into one hour without tolerance review,
- escalating frequency before route and meal context are stabilized.
Cross-site references
Uncertainty
- Evidence is limited on exact frequency cutoffs for each compound class.
- Evidence is limited on long-term adaptation when loading and maintenance overlap frequently.
How this appears in Unfair
Unfair applies frequency class profiles to recommend spacing and to trigger timing-based guardrails.
Clinical safety note
If high-frequency patterns begin causing new side effects, reduce cadence and review with care support.
Unfair uses this term in dose windows, one tap logging actions, journal entries, and reminder workflows.