Glossary
Stop Rule
Updated February 28, 2026
Stop rules are explicit if/then conditions for pausing a compound or stack.
Why it matters
They are meant to prevent escalation during likely adverse trends.
Non-negotiable stop points
- chest pain, severe palpitations, neurological confusion
- repeated severe GI distress with dehydration risk
- sustained high blood pressure or arrhythmia concerns
- escalating side effect severity over consecutive logs
If/then decision policy
- if severe warning appears, stop and seek urgent review
- if moderate warning persists, hold and request clinician input
- if mild, temporary warning appears, reduce complexity and monitor with tighter windows
Post-stop re-entry
After a stop event:
- review adverse context
- verify route, dose, and timing assumptions
- restart only after safety conditions are cleared and with conservative settings
Practical action step
Write stop triggers into one note before you begin each protocol so escalation decisions are already defined.
Uncertainty and limits
- Evidence is limited on exact threshold precision for every individual.
- Evidence is limited on re-entry timing where routines are highly variable.
Cross-site references
How this appears in Unfair
Stop rules directly gate recommendation progression, pause unsafe options, and adjust confidence messaging.
Clinical safety note
If unsure between hold and stop, choose conservative hold and clinical review first.
Unfair uses this term in warning banners, interaction prompts, and recommendation guardrails before stack activation.